Summary: A sort of American Don Quixote with less philosophical substance and more genocide
Woodrow Call and Gus McCrae, two retired Texas Rangers decide to take a herd of cattle from Texas to the north west, for no good reason other than they’re bored in a way that can only be alleviated by the risking of their own lives and those of others. On the way they cross paths with thieves, murderers, and impoverished and defeated Native Americans.

Obituaries of Larry McMurtry noted his admiration for Don Quixote, and this shows, superficially at least. Lonesome Dove is also about two characters wandering the countryside talking nonsense, though the meanderings of Gus and Call are considerably more sanguinary than those of Sancho and Quixote.
Lonesome Dove is a beloved novel and a Pulitzer-prize winner. But unlike Don Quixote, there seemed to me little beyond the bickering. McMurtry himself was reported to have lamented the impact of the book, hoping to have written about “a harsh time and some pretty harsh people, but, to the public at large, I had produced something nearer to an idealization… a kind of Gone With The Wind of the West”… which makes me like McMurtry rather more than his book, which is itself way better than Margaret Mitchell’s vile pro-slavery porn.
But whatever my reservations, Lonesome Dove is certainly an entertaining tome, its brutal characters not without charm or humour, and filled with some exciting moments of violence and with brilliant dialogue throughout.